Perfix^®: beyond weight loss - optimizing body composition

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Achieving a healthy body composition involves much more than just reducing body weight. Effective weight management should be pursued in a balanced and healthy manner to enhance quality of life, providing both physical and mental benefits. An essential goal in nutritional science is balancing effective fat reduction with the preservation of muscle mass, equally important for both women and men, and relevant across all ages. Recent clinical findings highlight Perfix^®, an innovative persimmon fruit extract developed by Euromed, as an effective nutritional solution that simultaneously promotes fat loss, supports muscle preservation and enhances overall body wellness.

PerFix^® is the latest ingredient in the category of Mediterranean fruit and vegetable extracts^®, derived from Mediterranean persimmons using a gentle, patented extraction process using ultra-purified water (Pure-Hydro^® process), that preserves key bioactive compounds such as tannins, polyphenols, and carotenoids. This persimmon extract provides a solution that goes beyond aesthetic improvements, offering consumers an option that prioritizes health and sustained results without associated adverse effects.

A recently published clinical trial by the Universidad Católica San Antonio de Murcia (UCAM) in Spain showed significant results in just 60 days, without any changes to diet or exercise. This randomized, double-blind, placebo-controlled study included 71 adults aged 18 to 65, all categorized as overweight or mildly obese. Over the course of 120 days, participants continued their regular dietary habits and physical activity routines, ensuring that the outcomes observed were exclusively attributable to the effects of the persimmon extract.

Supplementation with perFix^®, at 400 mg/day, demonstrated significant overall weight reduction, notably emphasizing fat loss. Participants taking perFix^® lost an average of 2.2 Kg of weight and 2.1 Kg of fat mass, compared to the placebo group, which saw increases in both. The perFix^® group also experienced reductions in waist (- 2.4 cm), abdominal (-2.2 cm), and hip circumference (-1.7 cm), as well as a 1.1 Kg reduction in trunk fat mass.

Remarkably, 90% of the weight loss was due to reduced body fat, highlighting the extract's precision in enhancing body composition and wellness. Importantly, the study confirmed perFix^®'s capability to preserve muscle mass during weight reduction, a key factor in maintaining physical strength, mobility, and overall health as individuals age.

Beyond body composition improvements, the trial also observed an increased excretion of dietary fats and significant antioxidant properties, suggesting an additional beneficial mechanism that supports healthy weight management. Participants also reported enhancements in quality of life parameters, indicating that perFix® not only benefits physical appearance and body metrics but contributes significantly to overall well-being and mental health.

Obesity remains a complex health challenge, frequently associated with metabolic inflammation and muscle loss, particularly when calorie restriction is inadequately managed. Current pharmacological approaches often result in unwanted muscle depletion, raising concerns about long-term health outcomes and the sustainability of weight loss. In this context, natural alternatives such as perFix^® offer promising results by significantly reducing inflammatory markers while preserving muscle mass, suggesting broader applications in managing both overweight and inflammatory metabolic conditions. This comprehensive approach contributes to healthier, more sustainable weight management and overall well-being.

Given the global rise in overweight, interventions like perFix^® represent a promising nutritional strategy for sustainable body wellness, effectively targeting the dual challenges of reducing fat mass while safeguarding muscle integrity. Considering that study participants did not alter their diet or physical activity, combining perFix^® with dietary interventions and appropriate exercise represents a promising strategy to enhance physical condition, improve appearance, support mental well-being, and ultimately achieve an integrated approach to a healthier lifestyle.

These findings highlight persimmon extract as a valuable ingredient in nutritional formulations aimed at supporting healthy aging and enhancing overall quality of life across all age groups.

Visit Euromed at Vitafoods Europe, at booth 3A24, from May 5 to May 7 in Barcelona.